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{{YTV|url=https://www.youtube.com/watch?v=Jon_mN4_yzM|description=Promotional video for the Genesis Mission}}
{{Tweet box|1993102758812303725|U.S. Department of Energy introduces the Genesis Mission}}


The '''Genesis Mission''' is a United States government initiative established by [https://www.federalregister.gov/documents/2025/11/28/2025-21665/launching-the-genesis-mission Executive Order 14363], signed by President [[Donald Trump]] on November 24, 2025.<ref name="eo">{{cite web |url=https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/ |title=Executive Order: Launching the Genesis Mission |date=November 24, 2025 |publisher=The White House}}</ref><ref name="factsheet">{{cite web |url=https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/ |title=Fact Sheet: President Donald J. Trump Unveils the Genesis Mission to Accelerate AI for Scientific Discovery |date=November 24, 2025 |publisher=The White House}}</ref> The program is administered by the [[Department of Energy]] (DOE) in coordination with the White House [[Office of Science and Technology Policy]].<ref name="doe">{{cite web |url=https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation |title=Energy Department Launches Genesis Mission to Transform American Science and Innovation |date=November 24, 2025 |publisher=U.S. Department of Energy}}</ref> Its primary objective is to double the productivity and impact of federally funded scientific research and development within a decade through large-scale application of [[artificial intelligence]] (AI), high-performance computing, and quantum technologies.<ref name="factsheet" /><ref name="genesis-site">{{cite web |url=https://genesis.energy.gov/ |title=Genesis Mission – Official Website |access-date=December 4, 2025 |publisher=U.S. Department of Energy}}</ref>
The initiative establishes a secure national platform that integrates the DOE’s 17 [[National Laboratories]], exascale supercomputers, and more than 100 petabytes of unique scientific data to train domain-specific AI foundation models and enable closed-loop autonomous experimentation.<ref name="doe" /><ref name="genesis-site" />
== Background and establishment ==
The Genesis Mission was formally announced on November 24, 2025.<ref name="eo" /><ref name="factsheet" /> It builds on a series of 2025 Trump administration executive actions promoting American AI leadership, including the January 2025 order removing regulatory barriers to AI development and the July 2025 “America’s AI Action Plan.”<ref name="factsheet" />
Administration officials have described the mission as a response to evidence of declining U.S. scientific productivity since the mid-20th century despite steadily increasing federal R&D investment, citing metrics such as falling rates of new drug approvals and transformative discoveries.<ref name="factsheet" /> The initiative is frequently compared by its proponents to historic national efforts including the [[Manhattan Project]] and [[Apollo program]].<ref name="doe" />
== Objectives ==
The mission pursues three overarching national priorities:<ref name="factsheet" /><ref name="genesis-site" />
* Achieving American energy dominance through AI-accelerated development of advanced nuclear fission, fusion energy, and modernized electric grids.
* Advancing fundamental discovery science in fields such as biotechnology, quantum information science, particle physics, and materials discovery.
* Strengthening national security by enhancing nuclear stockpile stewardship without physical testing, reducing reliance on foreign critical materials, and accelerating defense-related materials and manufacturing.
The administration has set an explicit goal of doubling the output and impact of U.S. federal research and development by approximately 2035.<ref name="doe" /><ref name="genesis-site" />
== Priority research domains ==
Official documents identify the following priority areas:<ref name="factsheet" />
* Biotechnology and life sciences
* [[Critical materials]] and supply-chain resilience
* Nuclear fission and fusion energy
* Space exploration technologies
* Quantum information science
* Semiconductors and microelectronics
== Infrastructure and technical approach ==
The core element is the “American Science and Security Platform,” a federated, secure infrastructure that combines:<ref name="eo" /><ref name="genesis-site" />
* DOE exascale supercomputing systems (Frontier, Aurora, El Capitan, etc.)
* Decades of proprietary experimental and simulation data
* High-throughput scientific instruments and robotic laboratories
* Private-sector AI models and cloud resources under strict government data controls
The platform is designed to support closed-loop scientific loops in which AI systems propose hypotheses, design experiments, interpret results, and iteratively improve models under human supervision.<ref name="genesis-site" />
== Leadership and governance ==
* Lead agency: United States Department of Energy<ref name="doe" />
* Genesis Mission Director: Under Secretary for Science and Innovation Dr. Darío Gil<ref name="doe" />
* Inter-agency coordination: Assistant to the President for Science and Technology Michael Kratsios (as of December 2025)<ref name="factsheet" />
* National security components: National Nuclear Security Administration<ref name="doe" />
== Private-sector partners ==
As of December 2025, the official Genesis Mission website lists the following industry collaborators:<ref name="genesis-site" />
* Anthropic
* NVIDIA
* OpenAI (government-focused offerings)
* IBM
* Microsoft
* AMD
* Amazon Web Services
* Google
* Oracle
Additional partnerships are expected to be announced.<ref name="genesis-site" />
== Implementation status ==
As of December 4, 2025:
* The DOE has mobilized its 17 National Laboratories for rapid stand-up.<ref name="doe" />
* A portfolio of at least 20 high-priority science and technology challenges is in preparation for release in early 2026.<ref name="eo" />
* Secure data-sharing and model-training agreements with industry partners are under negotiation.<ref name="genesis-site" />
* No dedicated congressional appropriation has been enacted; the program currently operates under existing DOE authorities and budgets.<ref name="factsheet" />
== Related initiatives ==
* American Science and Security Platform (the technical infrastructure created by the mission)
* Proposed GENESIS Act (legislation introduced December 2, 2025 by Rep. Mike Kennedy to codify and fund the mission; not enacted as of December 2025)
== References ==
{{Reflist}}
== External links ==
* [https://genesis.energy.gov/ Official website]
* [https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/ Executive Order establishing the Genesis Mission]
* [https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/ White House Fact Sheet]
* [https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation DOE announcement]
[[Category:Trump administration initiatives]]
[[Category:Artificial intelligence in the United States]]
[[Category:United States Department of Energy programs]]
[[Category:2025 in science]]
[[Category:Scientific supercomputing]]
[[Category:Executive orders of Donald Trump, 2025–2029]]

Latest revision as of 22:45, 4 December 2025

Template:YTV Template:Tweet box

The Genesis Mission is a United States government initiative established by Executive Order 14363, signed by President Donald Trump on November 24, 2025.[1][2] The program is administered by the Department of Energy (DOE) in coordination with the White House Office of Science and Technology Policy.[3] Its primary objective is to double the productivity and impact of federally funded scientific research and development within a decade through large-scale application of artificial intelligence (AI), high-performance computing, and quantum technologies.[2][4]

The initiative establishes a secure national platform that integrates the DOE’s 17 National Laboratories, exascale supercomputers, and more than 100 petabytes of unique scientific data to train domain-specific AI foundation models and enable closed-loop autonomous experimentation.[3][4]

Background and establishment

The Genesis Mission was formally announced on November 24, 2025.[1][2] It builds on a series of 2025 Trump administration executive actions promoting American AI leadership, including the January 2025 order removing regulatory barriers to AI development and the July 2025 “America’s AI Action Plan.”[2]

Administration officials have described the mission as a response to evidence of declining U.S. scientific productivity since the mid-20th century despite steadily increasing federal R&D investment, citing metrics such as falling rates of new drug approvals and transformative discoveries.[2] The initiative is frequently compared by its proponents to historic national efforts including the Manhattan Project and Apollo program.[3]

Objectives

The mission pursues three overarching national priorities:[2][4]

  • Achieving American energy dominance through AI-accelerated development of advanced nuclear fission, fusion energy, and modernized electric grids.
  • Advancing fundamental discovery science in fields such as biotechnology, quantum information science, particle physics, and materials discovery.
  • Strengthening national security by enhancing nuclear stockpile stewardship without physical testing, reducing reliance on foreign critical materials, and accelerating defense-related materials and manufacturing.

The administration has set an explicit goal of doubling the output and impact of U.S. federal research and development by approximately 2035.[3][4]

Priority research domains

Official documents identify the following priority areas:[2]

  • Biotechnology and life sciences
  • Critical materials and supply-chain resilience
  • Nuclear fission and fusion energy
  • Space exploration technologies
  • Quantum information science
  • Semiconductors and microelectronics

Infrastructure and technical approach

The core element is the “American Science and Security Platform,” a federated, secure infrastructure that combines:[1][4]

  • DOE exascale supercomputing systems (Frontier, Aurora, El Capitan, etc.)
  • Decades of proprietary experimental and simulation data
  • High-throughput scientific instruments and robotic laboratories
  • Private-sector AI models and cloud resources under strict government data controls

The platform is designed to support closed-loop scientific loops in which AI systems propose hypotheses, design experiments, interpret results, and iteratively improve models under human supervision.[4]

Leadership and governance

  • Lead agency: United States Department of Energy[3]
  • Genesis Mission Director: Under Secretary for Science and Innovation Dr. Darío Gil[3]
  • Inter-agency coordination: Assistant to the President for Science and Technology Michael Kratsios (as of December 2025)[2]
  • National security components: National Nuclear Security Administration[3]

Private-sector partners

As of December 2025, the official Genesis Mission website lists the following industry collaborators:[4]

  • Anthropic
  • NVIDIA
  • OpenAI (government-focused offerings)
  • IBM
  • Microsoft
  • AMD
  • Amazon Web Services
  • Google
  • Oracle

Additional partnerships are expected to be announced.[4]

Implementation status

As of December 4, 2025:

  • The DOE has mobilized its 17 National Laboratories for rapid stand-up.[3]
  • A portfolio of at least 20 high-priority science and technology challenges is in preparation for release in early 2026.[1]
  • Secure data-sharing and model-training agreements with industry partners are under negotiation.[4]
  • No dedicated congressional appropriation has been enacted; the program currently operates under existing DOE authorities and budgets.[2]

Related initiatives

  • American Science and Security Platform (the technical infrastructure created by the mission)
  • Proposed GENESIS Act (legislation introduced December 2, 2025 by Rep. Mike Kennedy to codify and fund the mission; not enacted as of December 2025)

References

  1. ↑ 1.0 1.1 1.2 1.3 "Executive Order: Launching the Genesis Mission". The White House. November 24, 2025. https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 "Fact Sheet: President Donald J. Trump Unveils the Genesis Mission to Accelerate AI for Scientific Discovery". The White House. November 24, 2025. https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/. 
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 "Energy Department Launches Genesis Mission to Transform American Science and Innovation". U.S. Department of Energy. November 24, 2025. https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation. 
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 "Genesis Mission – Official Website". U.S. Department of Energy. https://genesis.energy.gov/. 

External links

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