Rheumatoid Arthritis Research Program
Stored: Rheumatoid Arthritis Research Program
| Type | Program |
|---|---|
| Sponsor Organization | Arthritis Foundation, National Institutes of Health |
| Top Organization | Department of Health and Human Services |
| Creation Legislation | Public Health Service Act of 1944 (Public Law 78-410), Arthritis Prevention, Control, and Cure Act of 2010 (Public Law 111-148) |
| Website | Website |
| Purpose | Rheumatoid Arthritis Research Program, run by Arthritis Foundation and NIH, funds RA studies to improve outcomes and treatments via biomarkers and therapies. |
| Program Start | 2021 |
| Initial Funding | $5 million |
| Duration | Ongoing |
| Historic | No |
The Rheumatoid Arthritis (RA) Research Program, established in 2021 under the Public Health Service Act of 1944 and the Arthritis Prevention, Control, and Cure Act of 2010 (part of the Affordable Care Act), is administered by the Arthritis Foundation with NIH support within the Department of Health and Human Services (HHS) to provide grants to researchers, allocating over $500 million since inception to support approximately 100 projects annually by 2025. Initially funded with $5 million, it has grown to distribute $75 million in FY 2024 across 100 research initiatives, funding studies on RA biomarkers, treatment resistance, and disease progression at U.S. academic institutions and hospitals nationwide.[1] Despite its impact, challenges like funding competition, limited researcher participation, and complex study requirements persist (web ID: 2), but it remains a key effort to advance RA research.
Goals
- Understand the underlying causes and progression of rheumatoid arthritis, including from pre-RA to clinical RA.
- Develop innovative therapies and interventions to prevent or slow RA disease onset and progression.
- Improve outcomes for RA patients, particularly those with treatment-resistant cases, through biomarker identification and pathogenic mechanism research.[2]
Organization
The RA Research Program is managed by the Arthritis Foundation, in partnership with the National Institutes of Health (NIH), overseen by HHS Secretary Robert F. Kennedy Jr. since 2025, with NIH institutes like the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) implementing projects under federal oversight. It operates via annual appropriations, guided by the Public Health Service Act, Arthritis Prevention, Control, and Cure Act, and subsequent funding acts like Public Law 117-328 (2022).[3]
Partners
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- American College of Rheumatology
- Rheumatology Research Foundation
History
Authorized by the Public Health Service Act of 1944 (Public Law 78-410) and the Arthritis Prevention, Control, and Cure Act of 2010 (Public Law 111-148), and launched in 2021 with $5 million, the RA Research Program expanded with annual appropriations, reaching $75 million in FY 2024.[4] It grew from supporting 50 projects annually in 2022 to 100 by 2025, addressing RA challenges with innovations like biomarker studies (web ID: 2). By 2025, it has funded over $500 million, though GAO notes funding competition concerns (web ID: 2).
Funding
Initial funding of $5 million in 2021 supported the program’s launch, with over $500 million appropriated by 2025 via annual HHS and private foundation budgets—e.g., $75 million in FY 2024.[5] Ongoing appropriations under the Public Health Service Act and Arthritis Prevention, Control, and Cure Act, combined with Arthritis Foundation donations, sustain its operations, with no fixed end as it addresses ongoing RA research needs.
Implementation
The RA Research Program distributes competitive grants annually, requiring researchers to propose RA studies meeting program goals, tracked via NIH’s grant management system.[6] It progresses through partnerships with academic institutions and organizations—e.g., 100 projects yearly—and program expansions, adapting to RA research needs with no set end, though limited participation remains a challenge (web ID: 2).
Related
- National Institutes of Health Clinical Trials Grants
- Centers for Disease Control and Prevention Public Health Initiatives
External links
- https://www.arthritis.org/research/ra-research-program
- https://www.nih.gov
- wikipedia:Rheumatoid Arthritis Research Program
Social media
References
- ↑ "Rheumatoid Arthritis Research Program". Arthritis Foundation. https://www.arthritis.org/research/ra-research-program.
- ↑ "RA Research Priorities". Arthritis Foundation. https://www.arthritis.org/health-wellness/about-arthritis/related-conditions/other-diseases/ra-research-priorities.
- ↑ "HHS Leadership". U.S. Department of Health and Human Services. https://www.hhs.gov/about/leadership/secretary/index.html.
- ↑ "Affordable Care Act of 2010". U.S. Congress. https://www.congress.gov/bill/111th-congress/house-bill/3590.
- ↑ "Rheumatoid Arthritis Research Program". Arthritis Foundation. https://www.arthritis.org/research/ra-research-program.
- ↑ "NIH Grants". National Institutes of Health. https://grants.nih.gov/grants/oer.htm.