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{{YTV|url=https://www.youtube.com/watch?v=Jon_mN4_yzM|description=The Genesis Mission}}
{{YTV|url=https://www.youtube.com/watch?v=Jon_mN4_yzM|description=Promotional video for the Genesis Mission}}
{{Tweet box|1993102758812303725|U.S. Department of Energy introduces the Genesis Mission}}


{{Tweet box|1993102758812303725|Department of Energy introduces the Genesis Mission}}
The '''Genesis Mission''' is a United States government initiative established by Executive Order 14223, signed by President [[Donald Trump]] on November 24, 2025.<ref name="eo">{{cite web |url=https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/ |title=Executive Order: Launching the Genesis Mission |date=November 24, 2025 |publisher=The White House}}</ref><ref name="factsheet">{{cite web |url=https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/ |title=Fact Sheet: President Donald J. Trump Unveils the Genesis Mission to Accelerate AI for Scientific Discovery |date=November 24, 2025 |publisher=The White House}}</ref> The program is administered by the [[United States Department of Energy]] (DOE) in coordination with the White House [[Office of Science and Technology Policy]].<ref name="doe">{{cite web |url=https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation |title=Energy Department Launches Genesis Mission to Transform American Science and Innovation |date=November 24, 2025 |publisher=U.S. Department of Energy}}</ref> Its primary objective is to double the productivity and impact of federally funded scientific research and development within a decade through large-scale application of [[artificial intelligence]] (AI), high-performance computing, and quantum technologies.<ref name="factsheet" /><ref name="genesis-site">{{cite web |url=https://genesis.energy.gov/ |title=Genesis Mission – Official Website |access-date=December 4, 2025 |publisher=U.S. Department of Energy}}</ref>


<!-- {{YTV|url=https://www.youtube.com/live/TbPBEi8rpsg|description=Genesis Mission DOE Launch}} -->The '''Genesis Mission''' is a national [[initiative]] launched by the United States government, formalized by an [[Executive order|Executive Order]] signed by [[Donald Trump|President Donald J. Trump]] on [https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/ November 25, 2025]. This mission aims to revolutionize scientific research and accelerate discovery through the extensive application of [[artificial intelligence]] (AI). The Department of Energy (DOE) is central to this effort, tasked with leveraging its [[National laboratory|National Laboratories]], [[supercomputing capabilities]], and vast scientific data to create a cooperative system for research.  
The initiative establishes a secure national platform that integrates the DOE’s 17 [[National Laboratories]], exascale supercomputers, and more than 100 petabytes of unique scientific data to train domain-specific AI foundation models and enable closed-loop autonomous experimentation.<ref name="doe" /><ref name="genesis-site" />


Key components of the Genesis Mission include the establishment of a closed-loop AI experimentation platform within the DOE, designed to integrate national supercomputers and unique data assets to generate scientific foundation models and power robotic laboratories. The Assistant to the President for Science and Technology (APST) is responsible for coordinating this national initiative and integrating data and infrastructure across federal agencies. Collaboration with academia and private-sector innovators is also a critical aspect of the mission.
== Background and establishment ==
The Genesis Mission was formally announced on November 24, 2025.<ref name="eo" /><ref name="factsheet" /> It builds on a series of 2025 Trump administration executive actions promoting American AI leadership, including the January 2025 order removing regulatory barriers to AI development and the July 2025 “America’s AI Action Plan.”<ref name="factsheet" />


Priority research areas encompass (below) where chosen for their potential to enhance national, economic, and health security.  
Administration officials have described the mission as a response to evidence of declining U.S. scientific productivity since the mid-20th century despite steadily increasing federal R&D investment, citing metrics such as falling rates of new drug approvals and transformative discoveries.<ref name="factsheet" /> The initiative is frequently compared by its proponents to historic national efforts including the [[Manhattan Project]] and [[Apollo program]].<ref name="doe" />


* [[biotechnology]]
== Objectives ==
The mission pursues three overarching national priorities:<ref name="factsheet" /><ref name="genesis-site" />


* [[critical materials]]
* Achieving American energy dominance through AI-accelerated development of advanced nuclear fission, fusion energy, and modernized electric grids.
* Advancing fundamental discovery science in fields such as biotechnology, quantum information science, particle physics, and materials discovery.
* Strengthening national security by enhancing nuclear stockpile stewardship without physical testing, reducing reliance on foreign critical materials, and accelerating defense-related materials and manufacturing.


* [[nuclear fission]] and [[Fusion power|fusion energy]]
The administration has set an explicit goal of doubling the output and impact of U.S. federal research and development by approximately 2035.<ref name="doe" /><ref name="genesis-site" />


* [[space exploration]]
== Priority research domains ==
Official documents identify the following priority areas:<ref name="factsheet" />


* [[quantum information science]]
* Biotechnology and life sciences
* Critical materials and supply-chain resilience
* Nuclear fission and fusion energy
* Space exploration technologies
* Quantum information science
* Semiconductors and microelectronics


* [[semiconductors]] and [[microelectronics]]
== Infrastructure and technical approach ==
The core element is the “American Science and Security Platform,” a federated, secure infrastructure that combines:<ref name="eo" /><ref name="genesis-site" />


The [[Presidency of Donald Trump|Trump Administration]] anticipates that the Genesis Mission will significantly expand the productivity and impact of federal research and development within a decade by harnessing AI to overcome the perceived stagnation in scientific progress despite increased research budgets.
* DOE exascale supercomputing systems (Frontier, Aurora, El Capitan, etc.)
* Decades of proprietary experimental and simulation data
* High-throughput scientific instruments and robotic laboratories
* Private-sector AI models and cloud resources under strict government data controls


The website was designed by the [[National Design Studio]].  
The platform is designed to support closed-loop scientific loops in which AI systems propose hypotheses, design experiments, interpret results, and iteratively improve models under human supervision.<ref name="genesis-site" />


{{OU|text=genesis.energy.gov|url=https://genesis.energy.gov/}}
== Leadership and governance ==
* Lead agency: United States Department of Energy<ref name="doe" />
* Genesis Mission Director: Under Secretary for Science and Innovation Dr. Darío Gil<ref name="doe" />
* Inter-agency coordination: Assistant to the President for Science and Technology Michael Kratsios (as of December 2025)<ref name="factsheet" />
* National security components: National Nuclear Security Administration<ref name="doe" />


{{OU|text=whitehouse.gov|url=https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/}}
== Private-sector partners ==
 
As of December 2025, the official Genesis Mission website lists the following industry collaborators:<ref name="genesis-site" />
== Announcement ==
 
{{YTV|url=https://www.youtube.com/watch?v=FQ92hV1R4TA|description=Trump launches ‘Genesis Mission’ to supercharge US scientific AI innovation}}
 
Genesis Mission is building a new instrument for discovery, uniting human curiosity with machine intelligence to double our scientific output and tackle humanity's greatest challenges.
 
== Focus ==
 
The Genesis Mission will focus on addressing three key challenges of national importance:  
 
* American energy dominance: The Genesis Mission will accelerate advanced nuclear, fusion, and grid modernization using AI to provide affordable, reliable, and secure energy for Americans.
 
* Advancing discovery science: Through DOE’s investment and collaboration with industry, America is building the quantum ecosystem that will power discoveries—and industries—for decades to come.
 
* Ensuring national security: DOE will create advanced AI technologies for national security missions, deploy systems to ensure the safety and reliability of the U.S. nuclear stockpile, and accelerate the development of defense-ready materials.
 
== Functionality ==
 
Genesis Mission leverages the Department of Energy's unique scientific datasets-spanning more than 100 petabytes of experimental and simulation data across every major domain of science—to double the pace of American research and innovation within a decade.
 
== Energy ==
 
=== Fusion ===
 
Fusion you can plug into
 
Harnessing the power of the stars to deliver abundant, affordable energy. Through real-time collaboration between scientists, supercomputers, and AI systems, researchers can design, test, and stabilize fusion reactors far faster than ever before, accelerating the realization of sustainable fusion power.
 
=== Nuclear ===
 
Advanced nuclear, faster and safer
 
Creating a new generation of more efficient reactor designs, including new modular reactors, that provide reliable, around the clock energy. Engineers and AI tools work together to optimize reactor design, materials, licensing and operations, shortening development timelines while strengthening safety and performance.
 
=== Grid ===
 
An intelligent, resilient grid
 
Building a power network that grows as fast as the technologies it fuels. By combining human expertise in energy planning with AI-enabled forecasting and simulation, teams can modernize the nation's grid, improving reliability and accelerating deployment of new infrastructure.
 
== Discovery Science ==
 
=== Molecules ===
 
Seeing molecules in action
 
Revealing chemical and biological processes as they unfold in real time. AI will work with ultrafast experiments to observe molecular dynamics and uncover insights that accelerate breakthroughs in materials and medicine.
 
=== Particles ===
 
Understanding the universe, from quarks to cosmos
 
Connecting the smallest particles to the largest structures in existence. Physicists, guided by AI tools that reason across astronomical and particle-physics data, work together to test new theories about dark matter, dark energy, and the laws of nature.
 
=== Quantum ===
 
Discovering new quantum algorithms
 
Unlocking the next frontier of computation. AI serves as a reasoning partner for researchers, generating and verifying new classes of quantum algorithms while scientists interpret and validate the results, bringing practical quantum computing closer to reality.
 
== National Security ==
 
=== Materials ===
 
Securing critical materials
 
Reducing dependence on foreign supply chains. Materials scientists and AI systems co-design substitutes, responsibly utilize Earth's resources, and recover rare elements from waste, building a stable, self-reliant foundation for the nation's future industries.
 
=== Manufacturing ===
 
Accelerating advanced manufacturing
 
Turning design into production at the speed of need. Engineers and AI-driven digital twins share a continuous feedback loop between design, sensors, and fabrication, cutting qualification time and boosting efficiencies.
 
=== Discovery ===
 
Discovering mission-ready materials
 
Delivering alloys, polymers, and composites vital to defense and industry. Human insight and AI-guided discovery converge to fuse simulation, literature mining, and autonomous labs, pointing toward a future where years of materials research could unfold in a fraction of the time.
 
== Essential Information and Guidance ==
 
=== What is Genesis Mission? ===
 
A national imitative led by the Department of Energy and its 17 National Laboratories to build the world's most powerful scientific platform to accelerate discover, strength national security, and drive energy innovation.
 
=== Why now? ===
 
We are in the midst of a revolution in computing, driven by artificial intelligence and quantum information technologies, that will transform how science is done.  Genesis Mission has the mission of doubling the productivity and impact of U.S. research and development by pairing scientists with intelligent systems that reason, simulate, and experiment at extraordinary speed.
 
=== How does it work? ===
 
Genesis Mission will create a national discovery platform that unites the world’s most powerful supercomputers, AI systems, and emerging quantum technologies with the nation’s most advanced scientific instruments.  Together, they form and integrated infrastructure for scientific exploration – an intelligent network capable of sensing, simulation, and understanding nature at every scale.
 
By connecting these systems, Genesis Mission will transform how science is done.  It will generate a new class of high-fidelity data to train advanced AI models, empower researchers to solve the hardest scientific challenges, and accelerate discovery from years to months.  In doing so, it will serve as both a national accelerator for innovation and a providing ground for the next generation of AI, quantum, and robotics technologies.
 
=== What kinds of breakthroughs could it unlock? ===
 
From fusion energy and new materials to quantum computing and life-saving medicines, Genesis Mission expands what’s possible in energy, discovery science, and national security.
 
=== How is Genesis different from private-sector AI? ===
 
Unlike commercial models trained on the open internet, Genesis Mission draws from the government’s secure, multi-domain scientific data, decades of experiments unavailable anywhere else.  
 
=== Will Genesis Mission use AI to replace scientists? ===
 
No. Genesis Mission enables them.  It’s AI for discovery, not automation, helping researchers explore and understand the universe faster.  
 
=== Who's leading it? ===
 
The Department of Energy, in partnership with the White House [[Office of Science and Technology Policy]].  
 
=== Who are the partners in Genesis Mission? ===
 
Genesis Mission brings together the Department of Energy’s 17 National Laboratories with America’s leading technology and industrial companies—including pioneers in artificial intelligence, computing, materials, and energy—to build the most powerful scientific platform in history.
 
These collaborators include organizations such as 


* Anthropic
* NVIDIA
* NVIDIA
 
* OpenAI (government-focused offerings)
* [[Immunology|IBM]]
* IBM
 
* Microsoft
* [[Microsoft Power Platform|Microsoft]]
 
* [[Google DeepMind|Google]]
 
* [[Amazon Web Services]]
 
* [[OpenAI for Government]]
 
* AMD
* AMD
* Amazon Web Services
* Google
* Oracle


* GE Vernova
Additional partnerships are expected to be announced.<ref name="genesis-site" />
 
* Dell Technologies


Together, they represent the full strength of the U.S. innovation ecosystem, uniting public and private sectors to accelerate discovery and maintain America’s scientific and technological leadership.
== Implementation status ==
As of December 4, 2025:


=== How can people get involved? ===
* The DOE has mobilized its 17 National Laboratories for rapid stand-up.<ref name="doe" />
* A portfolio of at least 20 high-priority science and technology challenges is in preparation for release in early 2026.<ref name="eo" />
* Secure data-sharing and model-training agreements with industry partners are under negotiation.<ref name="genesis-site" />
* No dedicated congressional appropriation has been enacted; the program currently operates under existing DOE authorities and budgets.<ref name="factsheet" />


Genesis Mission is a movement to transform how science is done. DOE will open parts of the Genesis Mission platform to qualified researchers, innovators, and companies, ensuring the benefits of this national effort are shared across the American scientific ecosystem.
== Related initiatives ==
* American Science and Security Platform (the technical infrastructure created by the mission)
* Proposed GENESIS Act (legislation introduced December 2, 2025 by Rep. Mike Kennedy to codify and fund the mission; not enacted as of December 2025)


== Quotes ==
== References ==
 
{{Reflist}}
“Throughout history, from the Manhattan Project to the Apollo mission, our nation’s brightest minds and industries have answered the call when their nation needed them,” said '''U.S. Secretary of Energy Chris Wright.''' “Today, the United States is calling on them once again. Under President Trump’s leadership, the Genesis Mission will unleash the full power of our National Laboratories, supercomputers, and data resources to ensure that America is the global leader in artificial intelligence and to usher in a new golden era of American discovery.”
 
'''Under Secretary for Science and Genesis Mission Director, Dr. Darío Gil:''' “The Genesis Mission marks a defining moment for the next era of American science. We are linking the nation’s most advanced facilities, data, and computing into one closed-loop system to create a scientific instrument for the ages, an engine for discovery that doubles R&D productivity and solves challenges once thought impossible.”  
 
'''Administrator of the National Nuclear Security Administration, Brandon Williams:''' “The Genesis Mission represents the next great chapter and an unparallelled opportunity for America’s scientific and national security leadership. “Building on decades of innovation and collaboration across our national laboratories, NNSA will leverage AI, quantum computing, and advanced data analytics that will strengthen our deterrents and ensure the United States maintains an unmatched strategic edge over our adversaries. Under President Trump’s leadership, this mission will embody the very best of American ingenuity, turning science and innovation into security.”
 
'''Chair of the National Laboratory Directors’ Council, Dr. John Wagner:''' “DOE’s National Laboratories are engines of discovery that keep the United States competitive and secure. The Genesis Mission unlocks the full potential of these institutions by giving our scientists and engineers tools to work at the speed of innovation. Our laboratories have always risen to meet the nation’s greatest challenges, and this initiative ensures we continue that legacy in the age of artificial intelligence.” 
 
== Related ==
 
* [[American Science and Security Platform]]


== External links ==
== External links ==
 
* [https://genesis.energy.gov/ Official website]
* https://genesis.energy.gov/
* [https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/ Executive Order establishing the Genesis Mission]
 
* [https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/ White House Fact Sheet]
* https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/
* [https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation DOE announcement]


[[Category:Trump administration initiatives]]
[[Category:Trump administration initiatives]]
[[Category:Artificial intelligence in the United States]]
[[Category:United States Department of Energy programs]]
[[Category:2025 in science]]
[[Category:Scientific supercomputing]]
[[Category:Executive orders of Donald Trump, 2025–2029]]

Revision as of 22:41, 4 December 2025

Template:YTV Template:Tweet box

The Genesis Mission is a United States government initiative established by Executive Order 14223, signed by President Donald Trump on November 24, 2025.[1][2] The program is administered by the United States Department of Energy (DOE) in coordination with the White House Office of Science and Technology Policy.[3] Its primary objective is to double the productivity and impact of federally funded scientific research and development within a decade through large-scale application of artificial intelligence (AI), high-performance computing, and quantum technologies.[2][4]

The initiative establishes a secure national platform that integrates the DOE’s 17 National Laboratories, exascale supercomputers, and more than 100 petabytes of unique scientific data to train domain-specific AI foundation models and enable closed-loop autonomous experimentation.[3][4]

Background and establishment

The Genesis Mission was formally announced on November 24, 2025.[1][2] It builds on a series of 2025 Trump administration executive actions promoting American AI leadership, including the January 2025 order removing regulatory barriers to AI development and the July 2025 “America’s AI Action Plan.”[2]

Administration officials have described the mission as a response to evidence of declining U.S. scientific productivity since the mid-20th century despite steadily increasing federal R&D investment, citing metrics such as falling rates of new drug approvals and transformative discoveries.[2] The initiative is frequently compared by its proponents to historic national efforts including the Manhattan Project and Apollo program.[3]

Objectives

The mission pursues three overarching national priorities:[2][4]

  • Achieving American energy dominance through AI-accelerated development of advanced nuclear fission, fusion energy, and modernized electric grids.
  • Advancing fundamental discovery science in fields such as biotechnology, quantum information science, particle physics, and materials discovery.
  • Strengthening national security by enhancing nuclear stockpile stewardship without physical testing, reducing reliance on foreign critical materials, and accelerating defense-related materials and manufacturing.

The administration has set an explicit goal of doubling the output and impact of U.S. federal research and development by approximately 2035.[3][4]

Priority research domains

Official documents identify the following priority areas:[2]

  • Biotechnology and life sciences
  • Critical materials and supply-chain resilience
  • Nuclear fission and fusion energy
  • Space exploration technologies
  • Quantum information science
  • Semiconductors and microelectronics

Infrastructure and technical approach

The core element is the “American Science and Security Platform,” a federated, secure infrastructure that combines:[1][4]

  • DOE exascale supercomputing systems (Frontier, Aurora, El Capitan, etc.)
  • Decades of proprietary experimental and simulation data
  • High-throughput scientific instruments and robotic laboratories
  • Private-sector AI models and cloud resources under strict government data controls

The platform is designed to support closed-loop scientific loops in which AI systems propose hypotheses, design experiments, interpret results, and iteratively improve models under human supervision.[4]

Leadership and governance

  • Lead agency: United States Department of Energy[3]
  • Genesis Mission Director: Under Secretary for Science and Innovation Dr. Darío Gil[3]
  • Inter-agency coordination: Assistant to the President for Science and Technology Michael Kratsios (as of December 2025)[2]
  • National security components: National Nuclear Security Administration[3]

Private-sector partners

As of December 2025, the official Genesis Mission website lists the following industry collaborators:[4]

  • Anthropic
  • NVIDIA
  • OpenAI (government-focused offerings)
  • IBM
  • Microsoft
  • AMD
  • Amazon Web Services
  • Google
  • Oracle

Additional partnerships are expected to be announced.[4]

Implementation status

As of December 4, 2025:

  • The DOE has mobilized its 17 National Laboratories for rapid stand-up.[3]
  • A portfolio of at least 20 high-priority science and technology challenges is in preparation for release in early 2026.[1]
  • Secure data-sharing and model-training agreements with industry partners are under negotiation.[4]
  • No dedicated congressional appropriation has been enacted; the program currently operates under existing DOE authorities and budgets.[2]

Related initiatives

  • American Science and Security Platform (the technical infrastructure created by the mission)
  • Proposed GENESIS Act (legislation introduced December 2, 2025 by Rep. Mike Kennedy to codify and fund the mission; not enacted as of December 2025)

References

  1. ↑ 1.0 1.1 1.2 1.3 "Executive Order: Launching the Genesis Mission". The White House. November 24, 2025. https://www.whitehouse.gov/presidential-actions/2025/11/launching-the-genesis-mission/. 
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 "Fact Sheet: President Donald J. Trump Unveils the Genesis Mission to Accelerate AI for Scientific Discovery". The White House. November 24, 2025. https://www.whitehouse.gov/fact-sheets/2025/11/fact-sheet-president-donald-j-trump-unveils-the-genesis-missionto-accelerate-ai-for-scientific-discovery/. 
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 "Energy Department Launches Genesis Mission to Transform American Science and Innovation". U.S. Department of Energy. November 24, 2025. https://www.energy.gov/articles/energy-department-launches-genesis-mission-transform-american-science-and-innovation. 
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 "Genesis Mission – Official Website". U.S. Department of Energy. https://genesis.energy.gov/. 

External links

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