Research Project Grants


Stored: Research Project Grants

Research Project Grants
Type Program
Sponsor Organization National Institutes of Health
Top Organization Department of Health and Human Services
Creation Legislation Public Health Service Act of 1944 (Public Law 78-410)
Website Website
Purpose Research Project Grants, run by NIH, fund investigator-led biomedical research to boost knowledge, health, and tackle challenges with innovative studies.
Program Start 1945
Initial Funding $2 million
Duration Ongoing
Historic No

The Research Project Grants, established in 1945 under the Public Health Service Act of 1944, are administered by the National Institutes of Health (NIH) within the Department of Health and Human Services through its institutes and centers (e.g., National Cancer Institute, National Institute of Allergy and Infectious Diseases) to provide competitive grants to researchers, allocating over $300 billion since inception to support approximately 30,000 projects annually by 2025. Initially funded with $2 million, it has grown to distribute $25 billion in FY 2024 across 30,000 awards, funding research in areas like cancer, Alzheimer’s, and infectious diseases at academic institutions and research organizations nationwide.[1] Despite its impact, challenges like funding competition and administrative burdens persist (web ID: 7), but it remains a cornerstone of NIH’s research efforts.

Official Site

Goals

  • Advance scientific knowledge and innovation in biomedical and behavioral research.
  • Improve health outcomes and address public health challenges through investigator-initiated projects.
  • Support a diverse range of research, from basic science to clinical trials, to benefit human health.[2]

Organization

The Research Project Grants program is managed by NIH, overseen by Director Monica M. Bertagnolli since 2023, with institutes and centers implementing projects under federal oversight. It operates via annual appropriations, guided by the Public Health Service Act and subsequent funding acts like Public Law 117-328 (2022).[3]

Partners

History

Authorized by the Public Health Service Act of 1944 (Public Law 78-410) and launched in 1945 with $2 million, the Research Project Grants expanded with annual appropriations, reaching $25 billion in FY 2024.[4] It grew from funding 500 projects annually in 1946 to 30,000 by 2025, addressing health challenges with innovations like precision medicine initiatives (web ID: 7). By 2025, it has awarded over $300 billion, though GAO notes funding competition concerns (web ID: 7).

Funding

Initial funding of $2 million in 1945 supported the program’s launch, with over $300 billion appropriated by 2025 via annual HHS budgets—e.g., $25 billion in FY 2024.[5] Ongoing appropriations under the Public Health Service Act sustain its operations, with no fixed end as it addresses ongoing research needs.

Implementation

Research Project Grants distribute competitive grants annually, requiring investigators to submit research proposals, tracked via NIH’s eRA Commons system.[6] It progresses through partnerships with research institutions—e.g., 30,000 projects yearly—and program expansions, adapting to scientific needs with no set end, though funding competition remains a challenge (web ID: 7).

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